Women's Circle of Health


Black Women's Health Study


Carolina Breast Cancer Study


Multi-Ethnic Cohort Study


AMBER Consortium Researchers Gather to Discuss Study Successes and

Over 30 AMBER Consortium researchers from around the country met at the University of North Carolina, Chapel Hill to share study analysis and results and plan for the next exciting steps in examining this complex disease.

Currently, the AMBER Consortium has a combined total of over 8000 African American breast cancer cases and over 17,000 healthy controls in this cohort, making this the largest study of breast cancer in African American women in the country.


The African American Breast Cancer Epidemiology and Risk:
AMBER Consortium:


Numerous studies have demonstrated that women of African ancestry are more often diagnosed with early, aggressive breast cancers than women of European descent. African American women are more likely to be diagnosed with breast cancer before age 45 and are frequently diagnosed with tumors that are fast growing and lethal.  Younger African American women are more than twice as likely as white women to be diagnosed with a form of breast cancer that has poor prognosis and no therapeutic agents that work well.  It is startling that there are few explanations for this aggressive, poor-prognosis and early onset breast cancers in African American women. Progress in research is limited because existing studies of African American women lack the number of participants to investigate a full range of risk factors for breast cancer defined by early age at onset and type of tumor, and breast cancers that are very aggressive.

The AMBER Consortium was formed through a National Cancer Institute, Program Project Grant to combine four of the country's leading studies on African American women and breast cancer to study over 10,000 women. By combining the data from the Black Women's Health Study, The Women's Circle of Health Study, the Carolina Breast Cancer Study and the Multi-Ethnic Cohort Study this consortium will discover genetic, biologic, reproductive and behavioral risk factors for breast cancer.   Read More About Us

The research conducted by the AMBER Consortium is funded by the National Institutes of Health and Foundation grants: P01 CA151135 (CBA, JRP, AFO); R01 CA058420 (LR); UM1 CA164974 (JRP, LR); R01 CA098663 (JRP); R01 CA100598 (CBA); R01 CA185623 (EVB, CCH, KD); UM1 CA164973 (LLM, LKM, CAH); R01 CA54281 (LNK); R01 CA063464 (BH); P50 CA58223 (MAT, AFO); U01 CA179715 (MAT, AFO); Department of Defense Breast Cancer Research Program, Era of Hope Scholar Award Program W81XWH-08-1-0383 (CAH); the Susan G. Komen for the Cure Foundation (MAT, AFO); the Breast Cancer Research Foundation (CBA); and the University Cancer Research Fund of North Carolina (MAT, AFO)

Data on breast cancer cases were obtained from 24 state cancer registries (AZ, CA, CO, CT, DE, DC, FL, GA, IL, IN, KY, LA, MD, MA, MI, NJ, NY, NC, OK, PA, SC, TN, TX, and VA), and these results do not necessarily represent their views.

Amber: The color of optimism, amber is fossilized tree resin. The origins of amber come from deep within the pine tree, has attributed to its spiritual legacy.  The connectedness of the earth to the sky, the tree utilizes the sun's energy as a life source in producing this resin. Amber has been used in rituals through the centuries in ancient wisdom, as a healing stone allowing the body to heal itself.  Used by American Indians as a detoxifying element, it said to take negative energy and turn it to positive, purifying the body and spirit. Many ancient traditions have considered amber to be the stone of universal life force, as it encloses life within.